Symptoms
General symptoms
Besides the usual presenting symptoms of chest pain and shortness of breath, those with malignant mesothelioma may suffer a number of other clinical features, including:

Pleural effusion. This is a collection of fluid in the space between the parietal and visceral pleura. At the time of presentation, >50% of those with malignant mesothelioma have a large pleural effusion.
Fever, chills and sweats.
Weakness and malaise.
Weight loss.
Deteriorating 'performance status'.
Clotting disorders and pulmonary embolus (a blood clot in the lungs).
Anemia.